March 14, 2016

Research

 

Multidimensional biomechanical measurement

  • Invasive ovarian cancer cells
  • Nonlinear strain hardening of polymer films
  • Tissue & Protein mechanics
Microfluidic platforms for cell sorting into biomechanical phenotypes

  • Sorting by size and stiffness
  • Sorting by adhesion
  • Cell sorting by differences of viscoelasticty
  • Cell fractionation for ultra-high sample purity
 Microfluidic platform for cell transfection using volume exchange

  • Delivering nanoparticles
  • Delivering tracer molecules
  • Delivering Cas9 proteins
  • Delivering mRNA
Determining interaction energy wells and adhesion forces

  • Tip hovering by feedback to cantilever dynamics
  • Multivalent interactions in biology and biomedicine
Atomic force microscopy advancement

  • Microfluidic Liquid Cell
  • High-speed AFM imaging
  • High-resolution AFM imaging