Bioengineering and Microelectromechanical Systems

Our Focus

Multidimensional biomechanical measurement

Multidimensional biomechanical measurement •Invasive ovarian cancer cells •Nonlinear strain hardening of polymer films •Tissue & Protein mechanics

Microfluidic platform for cell transfection using volume exchange

• Delivering nanoparticles • Delivering tracer molecules • Delivering Cas9 proteins • Delivering mRNA

Microfluidic platforms for cell sorting into biomechanical phenotypes

•Sorting by stiffness •Sorting by size •Cell sorting by differences of viscoelasticty •Cell fractionation for ultra-high sample purity

Multifunctional particles for targeting and biological activation

•Biological Janus particles •Particles to activate the immune system

Inexpensive heat engines for pumping

•liquid piston Stirling engines •Single and Multicylinder engines •Flexible engines •Solar powered engines •High school education

Determining interaction energy wells and adhesion forces

•Tip hovering by feedback to cantilever dynamics •Multivalent interactions in biology and biomedicine

Atomic force microscopy advancement

•Microfluidic Liquid Cell •High-speed AFM imaging •High-resolution AFM imaging